Effects of Ecballium elatrium juice on serum bilirubin concentration in male rats

Abstract The effect of Ecballium elatrium juice on serum bilirubin concentration was examined in male rats. Jaundice was induced surgically by ligating the main bile duct. Intravenous administration of 0.05 ml of the juice two days after ligation resulted in a significant decrease in bilirubin concentration 24 h following the injection, while 0.1 ml produced a more pronounced decrease in bilirubin concentration 2.4, and 24 h after the injection. Intranasal administration of 0.1 ml of the juice also produced a significant decrease in bilirubin concentration and two doses produced more marked decrease.