Gluconeogenese a partir d'hepatocytes isoles de rats

A diet rich in proteins is given to rats for at least 20 days; this regimen causes metabolic modifications. They can be measured in vitro by the gluconeogenesis of hepatocytes from fasted animals. The presence of fatty acids in the incubation medium is necessary to reveal an increase in gluconeogene...

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Veröffentlicht in:Annals of nutrition and metabolism 1981, Vol.25 (2), p.90-96
Hauptverfasser: Lazrac, J, Feger, J, Davy, J, Gaudin-Harding, F, Agneray, J
Format: Artikel
Sprache:eng ; fre
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Zusammenfassung:A diet rich in proteins is given to rats for at least 20 days; this regimen causes metabolic modifications. They can be measured in vitro by the gluconeogenesis of hepatocytes from fasted animals. The presence of fatty acids in the incubation medium is necessary to reveal an increase in gluconeogenesis, which varies according to the substrate. There is a concomitant increase in fatty acid catabolism; this is in good correlation with ATP needs.
ISSN:0250-6807
1421-9697
DOI:10.1159/000176483