Glutahione-S-transferase-mediated methylthio displacement and turnover in the metabolism of pentachlorothioanisole by rats

Glutahione-S-transferase-mediated methylthio displacement and turnover in the metabolism of pentachlorothioanisole by rats

The metabolism of pentachlorothioanisole to bis-(methylthio)tetrachlorobenzene was shown to involve turnover of about 50% of the original methylthio group. Metabolites of the displaced methylthio group were methanesulphinic acid and sulphate in the urine, carbon dioxide in the expired air, and unide...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Xenobiotica 1991, Vol.21 (5), p.597-603
Hauptverfasser: Mulford, D.J, Bakke, J.E, Feil, V.J
Format: Artikel
Sprache:eng
Schlagworte:
glutathione transferase
hexachlorobenzene
metabolism
metabolites
organic sulfur compounds
quintozene
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
container_end_page 603
container_issue 5
container_start_page 597
container_title Xenobiotica
container_volume 21
creator Mulford, D.J
Bakke, J.E
Feil, V.J
description The metabolism of pentachlorothioanisole to bis-(methylthio)tetrachlorobenzene was shown to involve turnover of about 50% of the original methylthio group. Metabolites of the displaced methylthio group were methanesulphinic acid and sulphate in the urine, carbon dioxide in the expired air, and unidentified sulphur-containing compounds in the bile.
format Article
fullrecord <record><control><sourceid>fao</sourceid><recordid>TN_cdi_fao_agris_US201301768882</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>US201301768882</sourcerecordid><originalsourceid>FETCH-fao_agris_US2013017688823</originalsourceid><addsrcrecordid>eNqFy01uwjAQQGGrAqnh5wzMBSw5DgSzRtDuaddoIBNi5NjIMyDR0xck9qze5nsfqiirutaLlXUDVRgzX2lnF_NPNWI-G2Pq0tpC_X2Fq2DnUyS905IxcksZmXRPjUehBnqS7h7kYaDxfAl4pJ6iAMYG5JpjulEGH0E6elo8pOC5h9TC5cHw2IWU03PH6DkFgsMdMgpP1LDFwDR9daxm283P-lu3mPZ4yp73vztrysqUy9o5Z6v34h-K00xm</addsrcrecordid><sourcetype>Publisher</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype></control><display><type>article</type><title>Glutahione-S-transferase-mediated methylthio displacement and turnover in the metabolism of pentachlorothioanisole by rats</title><source>Taylor &amp; Francis</source><source>Taylor &amp; Francis Medical Library - CRKN</source><creator>Mulford, D.J ; Bakke, J.E ; Feil, V.J</creator><creatorcontrib>Mulford, D.J ; Bakke, J.E ; Feil, V.J</creatorcontrib><description>The metabolism of pentachlorothioanisole to bis-(methylthio)tetrachlorobenzene was shown to involve turnover of about 50% of the original methylthio group. Metabolites of the displaced methylthio group were methanesulphinic acid and sulphate in the urine, carbon dioxide in the expired air, and unidentified sulphur-containing compounds in the bile.</description><identifier>ISSN: 0049-8254</identifier><identifier>EISSN: 1366-5928</identifier><language>eng</language><subject>glutathione transferase ; hexachlorobenzene ; metabolism ; metabolites ; organic sulfur compounds ; quintozene</subject><ispartof>Xenobiotica, 1991, Vol.21 (5), p.597-603</ispartof><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,4010</link.rule.ids></links><search><creatorcontrib>Mulford, D.J</creatorcontrib><creatorcontrib>Bakke, J.E</creatorcontrib><creatorcontrib>Feil, V.J</creatorcontrib><title>Glutahione-S-transferase-mediated methylthio displacement and turnover in the metabolism of pentachlorothioanisole by rats</title><title>Xenobiotica</title><description>The metabolism of pentachlorothioanisole to bis-(methylthio)tetrachlorobenzene was shown to involve turnover of about 50% of the original methylthio group. Metabolites of the displaced methylthio group were methanesulphinic acid and sulphate in the urine, carbon dioxide in the expired air, and unidentified sulphur-containing compounds in the bile.</description><subject>glutathione transferase</subject><subject>hexachlorobenzene</subject><subject>metabolism</subject><subject>metabolites</subject><subject>organic sulfur compounds</subject><subject>quintozene</subject><issn>0049-8254</issn><issn>1366-5928</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1991</creationdate><recordtype>article</recordtype><recordid>eNqFy01uwjAQQGGrAqnh5wzMBSw5DgSzRtDuaddoIBNi5NjIMyDR0xck9qze5nsfqiirutaLlXUDVRgzX2lnF_NPNWI-G2Pq0tpC_X2Fq2DnUyS905IxcksZmXRPjUehBnqS7h7kYaDxfAl4pJ6iAMYG5JpjulEGH0E6elo8pOC5h9TC5cHw2IWU03PH6DkFgsMdMgpP1LDFwDR9daxm283P-lu3mPZ4yp73vztrysqUy9o5Z6v34h-K00xm</recordid><startdate>1991</startdate><enddate>1991</enddate><creator>Mulford, D.J</creator><creator>Bakke, J.E</creator><creator>Feil, V.J</creator><scope>FBQ</scope></search><sort><creationdate>1991</creationdate><title>Glutahione-S-transferase-mediated methylthio displacement and turnover in the metabolism of pentachlorothioanisole by rats</title><author>Mulford, D.J ; Bakke, J.E ; Feil, V.J</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-fao_agris_US2013017688823</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1991</creationdate><topic>glutathione transferase</topic><topic>hexachlorobenzene</topic><topic>metabolism</topic><topic>metabolites</topic><topic>organic sulfur compounds</topic><topic>quintozene</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Mulford, D.J</creatorcontrib><creatorcontrib>Bakke, J.E</creatorcontrib><creatorcontrib>Feil, V.J</creatorcontrib><collection>AGRIS</collection><jtitle>Xenobiotica</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Mulford, D.J</au><au>Bakke, J.E</au><au>Feil, V.J</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Glutahione-S-transferase-mediated methylthio displacement and turnover in the metabolism of pentachlorothioanisole by rats</atitle><jtitle>Xenobiotica</jtitle><date>1991</date><risdate>1991</risdate><volume>21</volume><issue>5</issue><spage>597</spage><epage>603</epage><pages>597-603</pages><issn>0049-8254</issn><eissn>1366-5928</eissn><abstract>The metabolism of pentachlorothioanisole to bis-(methylthio)tetrachlorobenzene was shown to involve turnover of about 50% of the original methylthio group. Metabolites of the displaced methylthio group were methanesulphinic acid and sulphate in the urine, carbon dioxide in the expired air, and unidentified sulphur-containing compounds in the bile.</abstract></addata></record>
fulltext fulltext
identifier ISSN: 0049-8254
ispartof Xenobiotica, 1991, Vol.21 (5), p.597-603
issn 0049-8254
1366-5928
language eng
recordid cdi_fao_agris_US201301768882
source Taylor & Francis; Taylor & Francis Medical Library - CRKN
subjects glutathione transferase
hexachlorobenzene
metabolism
metabolites
organic sulfur compounds
quintozene
title Glutahione-S-transferase-mediated methylthio displacement and turnover in the metabolism of pentachlorothioanisole by rats
url https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-02-03T04%3A39%3A35IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-fao&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Glutahione-S-transferase-mediated%20methylthio%20displacement%20and%20turnover%20in%20the%20metabolism%20of%20pentachlorothioanisole%20by%20rats&rft.jtitle=Xenobiotica&rft.au=Mulford,%20D.J&rft.date=1991&rft.volume=21&rft.issue=5&rft.spage=597&rft.epage=603&rft.pages=597-603&rft.issn=0049-8254&rft.eissn=1366-5928&rft_id=info:doi/&rft_dat=%3Cfao%3EUS201301768882%3C/fao%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/&rfr_iscdi=true