Subtyping Method for Escherichia coli Shiga Toxin (Verocytotoxin) 2 Variants and Correlations to Clinical Manifestations

Shiga toxin 2 (Stx2) from Shiga toxin-producing Escherichia coli (STEC) was subtyped by a method involving partial sequencing of the stxAB₂ operon. Of 255 strains from the Danish STEC cohort, all 20 cases of hemolytic-uremic syndrome were associated with subtype Stx2 (11 cases), subtype Stx2c (1 cas...

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Veröffentlicht in:Journal of Clinical Microbiology 2007-06, Vol.45 (6), p.2020-2024
Hauptverfasser: Persson, Søren, Olsen, Katharina E.P, Ethelberg, Steen, Scheutz, Flemming
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container_end_page 2024
container_issue 6
container_start_page 2020
container_title Journal of Clinical Microbiology
container_volume 45
creator Persson, Søren
Olsen, Katharina E.P
Ethelberg, Steen
Scheutz, Flemming
description Shiga toxin 2 (Stx2) from Shiga toxin-producing Escherichia coli (STEC) was subtyped by a method involving partial sequencing of the stxAB₂ operon. Of 255 strains from the Danish STEC cohort, all 20 cases of hemolytic-uremic syndrome were associated with subtype Stx2 (11 cases), subtype Stx2c (1 case), or the two combined (8 cases).
doi_str_mv 10.1128/JCM.02591-06
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source American Society for Microbiology; MEDLINE; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; PubMed Central
subjects Amino Acid Sequence
Bacteriology
Biological and medical sciences
Child
Denmark
Diarrhea - microbiology
Diarrhea - physiopathology
Escherichia coli
Escherichia coli - classification
Escherichia coli - genetics
Escherichia coli - pathogenicity
Escherichia coli Infections - microbiology
Escherichia coli Infections - physiopathology
Fundamental and applied biological sciences. Psychology
Genetic Variation
Hemolytic-Uremic Syndrome - microbiology
Hemolytic-Uremic Syndrome - physiopathology
Humans
Infectious diseases
Medical sciences
Microbiology
Miscellaneous
Molecular Sequence Data
Operon
Phylogeny
Sequence Analysis, DNA
Shiga Toxin 2 - chemistry
Shiga Toxin 2 - classification
Shiga Toxin 2 - genetics
Shiga Toxin 2 - metabolism
title Subtyping Method for Escherichia coli Shiga Toxin (Verocytotoxin) 2 Variants and Correlations to Clinical Manifestations
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