Adminitration of rhIL-2 upregulates HGF in the cirrhotic liver of partial hepatechtomized rats

Liver regeneration is a process involving highly organized and ordered tissue growth triggered by the loss liver tissue. This process has remained a fascinating topic in medicine. In this study, we examined the effects of recombinant human interleukin-2 in rats under cirrhotic conditions. thirty rat...

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Veröffentlicht in:Animal cells and systems 2013-06, Vol.17 (3)
Hauptverfasser: Jeon, M.A., Soonchunhyang university, Asan, Repulic of korea, Kwon, H.J., Soonchunhyang university, Asan, Repulic of korea, Kim, Y.H., Soonchunhyang university, Asan, Repulic of korea, Han, K.I., Soonchunhyang university, Asan, Repulic of korea, Nam, K.W., Soonchunhyang university, Asan, Repulic of korea, Baik, Y.J., BMI Korea Company, Asan, Republic of Korea, Lee, S.H., BMI Korea Company, Asan, Republic of Korea, Kim, W.J., Soonchunhyang university, Asan, Repulic of korea, Han, M.D., Soonchunhyang university, Asan, Repulic of korea
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Sprache:eng
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Zusammenfassung:Liver regeneration is a process involving highly organized and ordered tissue growth triggered by the loss liver tissue. This process has remained a fascinating topic in medicine. In this study, we examined the effects of recombinant human interleukin-2 in rats under cirrhotic conditions. thirty rats were divided into three groups, and liver cirrhosis was induced by injecting diethylnitrosamine for 2 weeks and CCl4 for 8 weeks. After induction of cirrhosis, rhIL2 was injected daily into their tail vein for three days and then hepatocyte growth factor , immunocytes in the blood, and TNF-a production were analyzed .
ISSN:1976-8354
2151-2485