Hypoglycemic Effect of Polysaccharide Isolated from Eclipta alba L

Hypoglycemic Effect of Polysaccharide Isolated from Eclipta alba L

The major polysaccharide, named EAP, was purified from the aerial parts of Eclipta alba by Sepharose CL-2B ion exchange chromatography and recycling HPLC. The molecular weight of EAP was estimated to be 20911.9 D by MALDI-TOFMS. In addition, the sugar composition was determined to be arabinose (23.6...

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Veröffentlicht in:Korean Journal of Pharmacognasy 2003-09, Vol.34 (3)
Hauptverfasser: Moon, Y.H, Woo, E.R, Lee, D.H. (Chosun University, Gwangju, Republic of Korea)
Format: Artikel
Sprache:kor
Schlagworte:
MOLECULAR WEIGHT
PESO MOLECULAR
POIDS MOLÉCULAIRE
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Zusammenfassung:The major polysaccharide, named EAP, was purified from the aerial parts of Eclipta alba by Sepharose CL-2B ion exchange chromatography and recycling HPLC. The molecular weight of EAP was estimated to be 20911.9 D by MALDI-TOFMS. In addition, the sugar composition was determined to be arabinose (23.6%), mannose (24.8%), galactose (12.3%), and glucose (41.3%), respectively, by GC analysis. The EAP decreased the blood sugar level, which was induced by alloxan in rats, dose dependently.
ISSN:0253-3073