Identification of a peptide mimic of bioactive gibberellins with affinity to GA 2-oxidase
Previously we reported the first example of peptide mimics of a small hydrophobic molecule, a phytohormone gibberellin. The second peptide mimic of gibberellin has been identified from random peptide libraries by its affinity to a type of catalyzing enzyme of gibberellins, which specifically recogni...
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| Veröffentlicht in: | Bioscience, biotechnology, and biochemistry biotechnology, and biochemistry, 2006-08, Vol.70 (8), p.2004-2006 |
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| container_end_page | 2006 |
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| container_issue | 8 |
| container_start_page | 2004 |
| container_title | Bioscience, biotechnology, and biochemistry |
| container_volume | 70 |
| creator | Sekimoto, H.(Tokyo Univ. (Japan)) Park, S.H Nakajima, M Yamaguchi, I Suzuki, Y |
| description | Previously we reported the first example of peptide mimics of a small hydrophobic molecule, a phytohormone gibberellin. The second peptide mimic of gibberellin has been identified from random peptide libraries by its affinity to a type of catalyzing enzyme of gibberellins, which specifically recognizes bioactive gibberellins. These results suggest that even hydrophobic compounds can be mimicked by peptides. |
| doi_str_mv | 10.1271/bbb.60141 |
| format | Article |
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Psychology</subject><subject>GA 2-oxidase</subject><subject>GIBBERELLIC ACID</subject><subject>gibberellin</subject><subject>Gibberellins - chemistry</subject><subject>HIDROFOBICIDAD</subject><subject>Hydrophobic and Hydrophilic Interactions</subject><subject>HYDROPHOBICITE</subject><subject>HYDROPHOBICITY</subject><subject>IDENTIFICACION</subject><subject>IDENTIFICATION</subject><subject>Mixed Function Oxygenases - chemistry</subject><subject>Molecular Mimicry</subject><subject>OXIDOREDUCTASES</subject><subject>OXIDORREDUCTASAS</subject><subject>OXYDOREDUCTASE</subject><subject>PEPTIDE</subject><subject>Peptide Library</subject><subject>peptide mimic</subject><subject>PEPTIDES</subject><subject>Peptides - chemistry</subject><subject>PEPTIDOS</subject><subject>random peptide library</subject><subject>Structure-Activity Relationship</subject><issn>0916-8451</issn><issn>1347-6947</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2006</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpt0M9rFDEUB_Agil2rB_8AJVAUPEzNm_ycYym2Vgp60IOnkGSSmjIzWZOsdf97s92VgngIgfB5L-99EXoJ5BR6Ce-ttaeCAINHaAWUyU4MTD5GKzKA6BTjcISelXJLSHvg8BQdgVCK8IGu0Per0S81huhMjWnBKWCD135d4-jxHOfodk82JuNq_OXxTbTWZz9NcSn4LtYf2IQQl1i3uCZ8eYb7Lv2Ooyn-OXoSzFT8i8N9jL5dfPh6_rG7_nx5dX523TlOhtoJoHJw0goqueUu9H6gwF0fnNodSSxxInhwTDgHTNqRtoXC6CVjgaqeHqO3-77rnH5ufKl6jsW1Cc3i06ZooaQcQIoGT_6Bt2mTlzabBsYGBZwI2tS7vXI5lZJ90OscZ5O3Gojepa1b2vo-7WZfHzpu7OzHB3mIt4E3B2CKM1PIZnGxPDjVM07pbge2d3EJKc_mLuVp1NVsp5T_FtH__f9qXxZM0uYmN_XpS0-IJITKXtE_uemgoA</recordid><startdate>20060801</startdate><enddate>20060801</enddate><creator>Sekimoto, H.(Tokyo Univ. 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Psychology</topic><topic>GA 2-oxidase</topic><topic>GIBBERELLIC ACID</topic><topic>gibberellin</topic><topic>Gibberellins - chemistry</topic><topic>HIDROFOBICIDAD</topic><topic>Hydrophobic and Hydrophilic Interactions</topic><topic>HYDROPHOBICITE</topic><topic>HYDROPHOBICITY</topic><topic>IDENTIFICACION</topic><topic>IDENTIFICATION</topic><topic>Mixed Function Oxygenases - chemistry</topic><topic>Molecular Mimicry</topic><topic>OXIDOREDUCTASES</topic><topic>OXIDORREDUCTASAS</topic><topic>OXYDOREDUCTASE</topic><topic>PEPTIDE</topic><topic>Peptide Library</topic><topic>peptide mimic</topic><topic>PEPTIDES</topic><topic>Peptides - chemistry</topic><topic>PEPTIDOS</topic><topic>random peptide library</topic><topic>Structure-Activity Relationship</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Sekimoto, H.(Tokyo Univ. 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| ispartof | Bioscience, biotechnology, and biochemistry, 2006-08, Vol.70 (8), p.2004-2006 |
| issn | 0916-8451 1347-6947 |
| language | eng |
| recordid | cdi_fao_agris_JP2007003728 |
| source | MEDLINE; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; Oxford University Press Journals All Titles (1996-Current); J-STAGE (Japan Science & Technology Information Aggregator, Electronic) Freely Available Titles - Japanese; Open Access Titles of Japan; Free Full-Text Journals in Chemistry |
| subjects | ACIDE GIBBERELLIQUE ACIDO GIBERELICO Biological and medical sciences BIOTECHNOLOGIE BIOTECHNOLOGY BIOTECNOLOGIA Catalysis Fundamental and applied biological sciences. Psychology GA 2-oxidase GIBBERELLIC ACID gibberellin Gibberellins - chemistry HIDROFOBICIDAD Hydrophobic and Hydrophilic Interactions HYDROPHOBICITE HYDROPHOBICITY IDENTIFICACION IDENTIFICATION Mixed Function Oxygenases - chemistry Molecular Mimicry OXIDOREDUCTASES OXIDORREDUCTASAS OXYDOREDUCTASE PEPTIDE Peptide Library peptide mimic PEPTIDES Peptides - chemistry PEPTIDOS random peptide library Structure-Activity Relationship |
| title | Identification of a peptide mimic of bioactive gibberellins with affinity to GA 2-oxidase |
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