Clinicopathological changes of induced levofloxacin toxicity in croiler chickens

Clinicopathological changes of induced levofloxacin toxicity in croiler chickens

Clinicopathological changes of graded dose levels of levofloxacin, a fluoroquinolone chemotherapeutic agent, were studied in croiler chickens. Birds administered orally with therapeutic dose of levofloxacin (60mg/kg b.wt.) developed mild gastrointestinal signs, anaemia, leucopenia, hypoglycemia, hyp...

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Veröffentlicht in:Indian journal of veterinary pathology 2009-12, Vol.33 (2)
Hauptverfasser: Kumar, Suman, Niyogi, D, Kumar, D, Singh, Y. Damodar, Sarkar, S, Mukhopadhayay, S.K
Format: Artikel
Sprache:eng
Schlagworte:
CHICKENS
http://www.fao.org/aos/agrovoc#c_1540
http://www.fao.org/aos/agrovoc#c_5631
http://www.fao.org/aos/agrovoc#c_7826
PATHOLOGIE
PATHOLOGY
PATOLOGIA
POLLO
POULET
TOXICIDAD
TOXICITE
TOXICITY
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Zusammenfassung:Clinicopathological changes of graded dose levels of levofloxacin, a fluoroquinolone chemotherapeutic agent, were studied in croiler chickens. Birds administered orally with therapeutic dose of levofloxacin (60mg/kg b.wt.) developed mild gastrointestinal signs, anaemia, leucopenia, hypoglycemia, hypoproteinemia and increased transaminase activity. Double and triple therapeutic doses produced severe gastrointestinal signs, partial loss of body weight, droopiness and leg weakness accompanied with significant (P0.05 or P0.01) anaemia, leucopenia, hypoglycemia, hypoproteinemia and increased transaminase activity.
ISSN:0250-4758