Tyromycin A: A novel inhibitor of leucine and cysteine aminopeptidases from Tyromyces lacteus

Tyromycin A: A novel inhibitor of leucine and cysteine aminopeptidases from Tyromyces lacteus

Tyromycin A, a new inhibitor of leucine and cysteine aminopeptidases has been isolated from mycelial cultures of the basidiomycete Tyromyces lacteus (Fr.) Murr. Its structure was established as 1,16-bis-[4-methyl-2,5-dioxo-3-furyl] hexadecane by spectral analysis and transformation into ester and im...

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Veröffentlicht in:Planta medica 1993, Vol.58 (1)
Hauptverfasser: Weber, W. (Kaiserslautern Univ. (Germany). Lehrbereich Biotechnologie), Semar, M, Anke, T, Bross, M, Steglich, W
Format: Artikel
Sprache:eng
Schlagworte:
AMINOPEPTIDASA
AMINOPEPTIDASE
aminopeptidase inhibitor
BASIDIOMYCOTINA
CISTEINA
citraconic anhydride derivative
CYSTEINE
ESTRUCTURA QUIMICA
INHIBICION
INHIBITION
LEUCINA
LEUCINE
PLANTAS MEDICINALES
PLANTE MEDICINALE
STRUCTURE CHIMIQUE
Tyromyces lacteus
Tyromycin A
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Zusammenfassung:Tyromycin A, a new inhibitor of leucine and cysteine aminopeptidases has been isolated from mycelial cultures of the basidiomycete Tyromyces lacteus (Fr.) Murr. Its structure was established as 1,16-bis-[4-methyl-2,5-dioxo-3-furyl] hexadecane by spectral analysis and transformation into ester and imide derivatives
ISSN:0032-0943
1439-0221