Immunologic efficiency of liquid cultural inactivated adjuvanted vaccine against rabies and canine parvovirus enteritis 'PARVORAB'

An important role in infection pathology of carnivorous animals is played by parvoviral enteritis of dogs, affecting also foxes, cats, polar foxes and other animals. The level of animals' deaths, caused by the disease, can achieve more than 80%. The most reliable method of prophylaxis of the disease is vaccination. Inactivated and live vaccines are usually used. Rabies is one more infection disease to be cured with the help of vaccine. Separate vaccination against rabies and parvoviral enteritis is rather expensive and time-consuming process, that's why development of bivalent vaccine against both infections is desired to be done. The article presents the results of studies of immunologic efficiency of liquid cultural inactivated adjuvanted vaccine against rabies and canine parvovirus enteritis 'PARVORAB' which contains strain KMIEV-14 b with titer 6.8–7.0 lg cultivated in cell culture VNK-21, virus PVES KMIEV-14 b in titer 7.0–8,0 log2 cultivated in cell culture CRFK, teotropin of 0.15% concentration (inactivator), Hidrocsal of 10% concentration (adjuvant). The vaccine is identified to be a safe, sterile and highly immunogenic preparation which is not inferior to foreign vaccines. The vaccine has been successfully tested and is recommended for practical use.