Novel heterocyclic compounds

PCT No. PCT/HU97/00069 Sec. 371 Date Apr. 27, 1999 Sec. 102(e) Date Apr. 27, 1999 PCT Filed Oct. 22, 1997 PCT Pub. No. WO98/18797 PCT Pub. Date May 7, 1998The invention relates to fused heterocyclic compounds with ring junction nitrogen atom of the formula: wherein Q stands for 2-indolizinyl, 2-imid...

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Hauptverfasser: GYOERGY FERENCZY, EGON KARPATI, BELA HEGEDUES, ESZTER THUROCZY NEE KALMAN, FERENC AUTH, MARGIT PELLIONISZ NEE PAROCZAI, ADAM SARKADI, JUDIT LASZY, SANDOR SZABO, GYOERGY DOMANY, ISTVAN LASZLOVSZKY, TIBOR ACS, BELA KISS, ERZSEBET LAPIS, MONIKA CSEJTEI, CSABA SZANTAY JR, FERENC TRISCHLER
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Sprache:eng
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Zusammenfassung:PCT No. PCT/HU97/00069 Sec. 371 Date Apr. 27, 1999 Sec. 102(e) Date Apr. 27, 1999 PCT Filed Oct. 22, 1997 PCT Pub. No. WO98/18797 PCT Pub. Date May 7, 1998The invention relates to fused heterocyclic compounds with ring junction nitrogen atom of the formula: wherein Q stands for 2-indolizinyl, 2-imidazo[1,2-a]pyridinyl, 2-imidazo[1,2-a]pyrimidinyl, 6-(2,3-dihydroimidazo[2,1-b]thiazol)-yl or 6-imidazo[2,1-b]thiazolyl group; and n is an integer from 2 to 4, as well as therapeutically useful salts thereof. The invention further relates to pharmaceutical compositions containing these compounds as well as a process for the preparation of the above compounds and compositions. The compounds of formula (I) exhibit mainly antipsychotic effects so the invention relates also to a method of treatment of schizophrenia, organic mental disorders, affective disorders, anxiety and personality disorders.