Picornavirus L proteinase and methods and making and using thereof

Methods of making and using Picornavirus L proteinase peptides (PLPPs) are provided, including, but not limited to, expression of DNA encoding all or a portion thereof, such as a Picornavirus L proteinase (PLP) and variants thereof, as well as methods for determining active sites and inhibitors of a...

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Hauptverfasser: HORST AHORN, DIETER BLAAS, ROBERT E RHOADS, ELIZABETH ZIEGLER, TIMOTHY SKERN, WOLFANG SOMMERGRUBER, HANS-DIETER LIEBIG, BARRY J LAMPHEAR, DEBRA WATERS, REGINA KITCHWEGER
Format: Patent
Sprache:eng
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Zusammenfassung:Methods of making and using Picornavirus L proteinase peptides (PLPPs) are provided, including, but not limited to, expression of DNA encoding all or a portion thereof, such as a Picornavirus L proteinase (PLP) and variants thereof, as well as methods for determining active sites and inhibitors of a PLP.