Pharmaceutical compounds

A diketopiperazine of formula (A): wherein one or both of R1 and R2, which may be the same or different, is: X, substituted phenyl, CH=C(W)V or cyclohexyl; and where appropriate, the other of R1 and R2 is an optionally substituted phenyl group X is a naphthyl group or an optionally substituted five-...

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Hauptverfasser: JUSTIN STEPHEN BRYANS, ADRIAN JOHN FOLKES, STEPHEN JAMES BROCCHINI, CHRISTOPHER JOHN LATHAM, JULIE ELIZABETH BRUMWELL
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creator JUSTIN STEPHEN BRYANS
ADRIAN JOHN FOLKES
STEPHEN JAMES BROCCHINI
CHRISTOPHER JOHN LATHAM
JULIE ELIZABETH BRUMWELL
description A diketopiperazine of formula (A): wherein one or both of R1 and R2, which may be the same or different, is: X, substituted phenyl, CH=C(W)V or cyclohexyl; and where appropriate, the other of R1 and R2 is an optionally substituted phenyl group X is a naphthyl group or an optionally substituted five- or six-membered saturated or unsaturated heterocyclic group W is hydrogen or a phenyl group; V is an optionally substituted phenyl group, and the pharmaceutically acceptable salts and esters thereof have activity as inhibitors of plasminogen activator inhibitor.
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subjects CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title Pharmaceutical compounds
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