Pharmaceutical compounds

A diketopiperazine of formula (A): wherein one or both of R1 and R2, which may be the same or different, is: X, substituted phenyl, CH=C(W)V or cyclohexyl; and where appropriate, the other of R1 and R2 is an optionally substituted phenyl group X is a naphthyl group or an optionally substituted five-...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser:	JUSTIN STEPHEN BRYANS, ADRIAN JOHN FOLKES, STEPHEN JAMES BROCCHINI, CHRISTOPHER JOHN LATHAM, JULIE ELIZABETH BRUMWELL
Format:	Patent
Sprache:	eng
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	A diketopiperazine of formula (A): wherein one or both of R1 and R2, which may be the same or different, is: X, substituted phenyl, CH=C(W)V or cyclohexyl; and where appropriate, the other of R1 and R2 is an optionally substituted phenyl group X is a naphthyl group or an optionally substituted five- or six-membered saturated or unsaturated heterocyclic group W is hydrogen or a phenyl group; V is an optionally substituted phenyl group, and the pharmaceutically acceptable salts and esters thereof have activity as inhibitors of plasminogen activator inhibitor.