Methods of treating cancer

This invention relates to methods of treating cancer in a mammal which comprise administering to said mammal a potentiating effective amount of AZT, or a pharmaceutically acceptable salt or ester thereof, with an effective amount of either an alkylating agent or a DNA intercalating agent. The prefer...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser:	DAVID STANLEY DUCH, BANGARU CHANDRASEKARAN
Format:	Patent
Sprache:	eng
Schlagworte:	ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAININGELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN,SULFUR, SELENIUM OR TELLURIUM CHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	This invention relates to methods of treating cancer in a mammal which comprise administering to said mammal a potentiating effective amount of AZT, or a pharmaceutically acceptable salt or ester thereof, with an effective amount of either an alkylating agent or a DNA intercalating agent. The preferred alkylating agent is melphalan while the preferred DNA intercalating agent is adriamycin.