Cycloalkyl- and heterocyclyl-substituted imidazolylpropenoic acid derivatives

Cycloalkyl- and heterocyclyl-substituted imidazolylpropenoic acid derivatives

Cycloalkyl- and heterocyclyl-substituted imidazolylpropenoic acid derivatives can be prepared by reaction of imidazolylaldehydes with appropriate carboxylic acid derivatives and subsequent dehydrogenation. The compounds can be employed as active ingredients in medicaments, in particular for the trea...

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Hauptverfasser: MATTHIAS MUELLER-GLIEMANN DR, ANDREAS KNORR DR, STANISLAV KAZDA PROF DR, WALTER HUEBSCH DR, RUDOL HANKO DR, MARTIN BEUCK DR, STEFAN WOHLFEIL DR, JUERGEN DRESSEL PH D, JOHANNES-PETER STASCH DR, THOMAS KRAEMER DR, ULRICH MUELLER DR, PETER FEY DR
Format: Patent
Sprache:eng
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Zusammenfassung:Cycloalkyl- and heterocyclyl-substituted imidazolylpropenoic acid derivatives can be prepared by reaction of imidazolylaldehydes with appropriate carboxylic acid derivatives and subsequent dehydrogenation. The compounds can be employed as active ingredients in medicaments, in particular for the treatment of hypertension and atherosclerosis.