N-phenylthiourea derivatives and pharmaceutical use thereof

The invention concerns the use of the compounds of formula I wherein the substituents have various significances, in free form or salt form as appropriate, in the treatment of atherosclerosis. It also concerns pharmaceutical compositions comprising a compound selected from a subgroup thereof. It fur...

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Bibliographische Detailangaben
Hauptverfasser: GARY MARK COPPOLA, ROBERT EDSON DAMON II
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:The invention concerns the use of the compounds of formula I wherein the substituents have various significances, in free form or salt form as appropriate, in the treatment of atherosclerosis. It also concerns pharmaceutical compositions comprising a compound selected from a subgroup thereof. It further concerns a subgroup of compounds thereof, which are novel, per se. The compounds of formula I can be prepared in conventional manner, e.g. by reaction of an isothiocyanate with an amine or conversion of an urea to a thiourea.