PROCESS FOR THE PREPARATION OF 1BETA-ETHYL-1-ALPHA-(HYDROXYMETHYL)-1,2,3,4,6,7,12 12BALPHA-OCTAHYDRO-INDOLO(2,3-A)QUINOLIZINE AND NOVEL INTERMEDIATES

PCT No. PCT/HU91/00046 Sec. 371 Date Jun. 25, 1992 Sec. 102(e) Date Jun. 25, 1992 PCT Filed Oct. 30, 1991 PCT Pub. No. WO92/07851 PCT Pub. Date May 14, 1992.The invention relates to a novel process for the preparation of (-) -1 beta -ethyl-1 alpha -(hydroxymethyl) - 1,2,3,4,6,7,12,12b alpha -octahyd...

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Hauptverfasser: JANOS KREIDL, GYOERGY VISKY, KATALIN NOGRADI, LASZLO CZIBULA, JUDIT BRILL (DECEASED), MARIA FARKAS NEE KIRJAK, IDA DEUTSCH NEE JUHASZ
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Sprache:eng
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Zusammenfassung:PCT No. PCT/HU91/00046 Sec. 371 Date Jun. 25, 1992 Sec. 102(e) Date Jun. 25, 1992 PCT Filed Oct. 30, 1991 PCT Pub. No. WO92/07851 PCT Pub. Date May 14, 1992.The invention relates to a novel process for the preparation of (-) -1 beta -ethyl-1 alpha -(hydroxymethyl) - 1,2,3,4,6,7,12,12b alpha -octahydro-indolo[2,3-a]quinolizine of the formula (I) (I) and to novel intermediates obtained in this process. The compound of the formula (I) prepared by the process of the invention possesses a peripheral vasodilator effect.