NOVEL NAPHTHALENE CARBOXYLIC ACIDS

The invention relates to substituted naphthalene carboxylic acid derivatives of the formula I wherein one of R1 and R2 is and the other is hydrogen, wherein R is hydrogen or lower alkyl, R10 is hydrogen or lower alkyl, and m is 0 or 1 A is A' wherein R3 is hydrogen or acyl, R4 is a hydrogen, ha...

Ausführliche Beschreibung

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Hauptverfasser: MATTHEW CARSON, RU-JEN LEE HAN, RONALD ANDREW LEMAHIEU
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:The invention relates to substituted naphthalene carboxylic acid derivatives of the formula I wherein one of R1 and R2 is and the other is hydrogen, wherein R is hydrogen or lower alkyl, R10 is hydrogen or lower alkyl, and m is 0 or 1 A is A' wherein R3 is hydrogen or acyl, R4 is a hydrogen, halogen, lower alkyl, aryl or cycloalkyl, R5 and R6 independently are hydrogen or halogen, and n is an integer from 2-10, or A is A'' wherein R3 is hydrogen or acyl, R7 is hydrogen or lower alkyl, R8 and R9, independently, are hydrogen, lower alkyl or halogen, t is 0 or 1, and n is an integer from 2-10, and, when R10 is lower alkyl, enantiomers and racemates thereof, and, when R is hydrogen, salts thereof with pharmaceutically acceptable bases.