COMPOUNDS FOR USE IN MEDICINE

The present invention is concerned with methods for the prophylaxis, treatment and diagnosis of pulmonary hypertension which comprise the administrative of an effective amount of a compound of formula (I) (I) wherein a is an integer of from 1 to 3; X and Y, which may be the same or different, are se...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: KENNETH BRUCE KLEIN, BRENDAN JOSEPH RICHARD WHITTLE, WALKER ANDERSON LONG, JAMES WALKER CROW, ANJANEYULU SEETHARAM TADEPALLI
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:The present invention is concerned with methods for the prophylaxis, treatment and diagnosis of pulmonary hypertension which comprise the administrative of an effective amount of a compound of formula (I) (I) wherein a is an integer of from 1 to 3; X and Y, which may be the same or different, are selected from -O- and -CH2-; R is -(CH2)5R1 wherein R1 is hydrogen or methyl, or R is cyclohexyl, or R is -CH(CH3)CH2C 3BOND CCH3; and the dotted line represents an optional double bond; or of a physiologically acceptable salt or acid derivative thereof. Medicaments and diagnostic aids for use in the methods of the invention are also within the scope of the invention.