PROCESS FOR OBTAINING ENANTIOMERS OF 2-ARYLPROPIONIC ACIDS

PROCESS FOR OBTAINING ENANTIOMERS OF 2-ARYLPROPIONIC ACIDS

Enantiomers of 2-arylpropionic acids are obtained by reaction of a racemic mixture thereof with an amine enantiomer by converting the racemate of 2-arylpropionic acid into the diastereomeric salts using an optically active form of threo-1-p-nitrophenyl-2-aminopropane- 1,3-diol, separating these salt...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: GOTTFRIED BLASCHKE, KARL-ERNST SCHULTE
Format: Patent
Sprache:eng
Schlagworte:
ACYCLIC OR CARBOCYCLIC COMPOUNDS
APPARATUS THEREFOR
CHEMISTRY
GENERAL METHODS OF ORGANIC CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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Beschreibung
Zusammenfassung:Enantiomers of 2-arylpropionic acids are obtained by reaction of a racemic mixture thereof with an amine enantiomer by converting the racemate of 2-arylpropionic acid into the diastereomeric salts using an optically active form of threo-1-p-nitrophenyl-2-aminopropane- 1,3-diol, separating these salts and converting the pure diastereomers thus obtained into the free acids of the enantiomeric forms of 2-arylpropionic acid or salts thereof.