PHARMACEUTICAL COMPOSITIONS

The present invention provides a pharmaceutical granule composition comprising cimetidine and, as a granulating agent and taste-masking agent, an ester of a polyhydroxy compound, and where desired a palatable pharmaceutically acceptable emulsifier. Particular esters are glycerol esters. The granules...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: EBERHARD FRITZ GOTTWALD, DAVID MAYRON, HERMANN PETER OSTERWALD, HORST MANFRED MACHOCZEK
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:The present invention provides a pharmaceutical granule composition comprising cimetidine and, as a granulating agent and taste-masking agent, an ester of a polyhydroxy compound, and where desired a palatable pharmaceutically acceptable emulsifier. Particular esters are glycerol esters. The granules of the present invention can be used in the preparation of chewable tablets which have good palatability and bioavailability.