NOVEL PYRIDAZINAMINE DERIVATIVES

Novel pyridazinamine derivatives of formula wherein R is hydrogen, C1-6alkyl, halo, hydroxy, mercapto, trifluoromethyl, amino, mono or di(C1-6alkyl)amino, cyano, C1-6alkyloxy, aryloxy, arylC1-6alkyloxy, C1-6alkylthio, arylthio, C1-6alkylsulfinyl, C1-6alkylsulfonyl, arylsulfinyl, aryllsulfonyl, C1-6a...

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Hauptverfasser: MARCEL JOZEF MARIA VAN DER AA, RAYMOND ANTOINE STOCKBROEKX, GILBERT ARTHUR JULES GRAUWELS, MARCEL GEREBERNUS MARIA LUYCKX
Format: Patent
Sprache:eng
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Zusammenfassung:Novel pyridazinamine derivatives of formula wherein R is hydrogen, C1-6alkyl, halo, hydroxy, mercapto, trifluoromethyl, amino, mono or di(C1-6alkyl)amino, cyano, C1-6alkyloxy, aryloxy, arylC1-6alkyloxy, C1-6alkylthio, arylthio, C1-6alkylsulfinyl, C1-6alkylsulfonyl, arylsulfinyl, aryllsulfonyl, C1-6alkyloxycarbonyl, C1-6alkylcarbonyl or aryl; R and R each independently are hydrogen or C1-6alkyl, or R and R combined may form a bivalent radical of formula -CH=CH-CH=CH- G is a bivalent radical of formula X is O, S, NR or a direct bond; said R being hydrogen or C-6alkyl; the pharmaceutically acceptable acid addition salts and possible stereochemically isomeric forms thereof, which compounds are anti-virals; pharmaceutical compositions containing such compounds as an active ingredient and methods of preparing said compounds and pharmaceutical compositions.