RECOMBINANT EUKARYOTIC CELLS PRODUCING INTERLEUKIN-2,PROCESS AND VECTORS FOR THEIR PREPARATION AND PROCESS FOR THE PREPARATION OF INTERLEUKIN-2

RECOMBINANT EUKARYOTIC CELLS PRODUCING INTERLEUKIN-2,PROCESS AND VECTORS FOR THEIR PREPARATION AND PROCESS FOR THE PREPARATION OF INTERLEUKIN-2

Recombinant eukaryotic cells producing interleukin-2 which contain, with the means needed for their expression, a DNA sequence coding for dihydrofolate reductase and a DNA sequence coding for a hybrid precursor of interleukin-2 in which the peptide signal is that of one of the natural precursors of...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: JOHANNES LUPKER, WILLEM ROSKAM, BRIGITTE MILOUX
Format: Patent
Sprache:eng
Schlagworte:
BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS THEREOF
CULTURE MEDIA
ENZYMOLOGY
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
ORGANIC CHEMISTRY
PEPTIDES
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SPIRITS
VINEGAR
WINE
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Beschreibung
Zusammenfassung:Recombinant eukaryotic cells producing interleukin-2 which contain, with the means needed for their expression, a DNA sequence coding for dihydrofolate reductase and a DNA sequence coding for a hybrid precursor of interleukin-2 in which the peptide signal is that of one of the natural precursors of the human growth hormone. The invention also relates to the process and the vectors for obtaining these cells and to the process for obtaining interleukin-2 from the latter. Application: production of interleukin-2.