A PHARMACEUTICAL COMPOUNT CONTAINING NIFEDIPINE

The invention concerns a pharmaceutical compound containing Nifedipine, combined with a physiologically tolerated substance capable of forming a complex with Nifedipine. This increases the solubility of Nifedipine. The complexing substance is preferably a xanthine, especially Theophylline, which giv...

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Bibliographische Detailangaben
Hauptverfasser:	HELMUT RACKUR, GUENTHER KOCH, UWE DETHLEFSEN
Format:	Patent
Sprache:	eng
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The invention concerns a pharmaceutical compound containing Nifedipine, combined with a physiologically tolerated substance capable of forming a complex with Nifedipine. This increases the solubility of Nifedipine. The complexing substance is preferably a xanthine, especially Theophylline, which gives a surprising synergistic pharmacological combinatory effect. The invention further concerns a pharmaceutical preparation, especially useful for the Nifedipine/Theophylline combination, and a method for producing such preparations.