DETECTION OF INFLAMMATION AND NOVEL ANTIBODIES THEREFOR

An assay, test kit and novel antibodies for use therein are provided for detecting the presence of inflammation caused, for instance, by infectious disease or immune dysfunction, measures the level of IL-1 in body fluid, such as serum. Various assay techniques may be employed including direct assays...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: KATHRYN SUSAN PRICKETT, PAUL JEROME CONLON
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:An assay, test kit and novel antibodies for use therein are provided for detecting the presence of inflammation caused, for instance, by infectious disease or immune dysfunction, measures the level of IL-1 in body fluid, such as serum. Various assay techniques may be employed including direct assays, competitive assays and double determinant assays. The assay and test kit employs novels polyclonal or monoclonal antibodies specific for unique antigenic sites on the IL-1 protein or IL-1 peptide.