PYRAZOLE DERIVATIVES WITH AN ERGOLINE SKELETON,THEIR ACID ADDITION SALTS,AND A PROCESS FOR THE PREPARATION THEREOF
The subject matter of the application are pyrazole derivatives with an ergoline skeleton of general formula wherein x...y stands for a group of formula R means a hydrogen atom or a methyl group, R1 represents a hydrogen atom or a C1-4-alkyl, carbethoxy or pyridyl group and either R2 stands for a hyd...
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creator | ERZSEBET MAGO NEE KARACSONY ALIZ DRUGA LAJOS TOLDY ANDRIAS RONAI GYOERGY CSEH ILONA BERZETEI JOZSEF BORSY TIVADAR RETTEGI |
description | The subject matter of the application are pyrazole derivatives with an ergoline skeleton of general formula wherein x...y stands for a group of formula R means a hydrogen atom or a methyl group, R1 represents a hydrogen atom or a C1-4-alkyl, carbethoxy or pyridyl group and either R2 stands for a hydrogen atom or a C1-4-alkyl, allyl, C2-4-oxoalkyl, C2-4-hydroxyalkyl or C2-4-hydroxyiminoalkyl group and R3 means a hydrogen atom or a C1-4-alkyl, hydroxy or pyridyl group or R2 and R3 together stand for a group of general formula II of claim 1, as well as their salts as well as a process for preparing them and pharmaceutical compositions containing these compounds. The above compounds above all are potent PGF2 alpha receptor antagonists. |
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The above compounds above all are potent PGF2 alpha receptor antagonists.</abstract><edition>3</edition><oa>free_for_read</oa></addata></record> |
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subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
title | PYRAZOLE DERIVATIVES WITH AN ERGOLINE SKELETON,THEIR ACID ADDITION SALTS,AND A PROCESS FOR THE PREPARATION THEREOF |
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