NEW PIPERIDINE DERIVATIVES OF INDOLE

NEW PIPERIDINE DERIVATIVES OF INDOLE

1510765 Piperidinoalkylindoles BOEHRINGER MANNHEIM GmbH 4 Nov 1976 [7 Nov 1975] 45918/76 Heading C2C The invention comprises compounds of formula and their pharmacologically compatible salts, wherein R 1 , R 2 and R 3 are each H or C 1-6 alkyl, or R 3 may be halogen or C 1-6 alkoxy, and X is C 2 or...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: STACH K, THIEL M, FRIEBE W, SPONER G, DIETMANN K
Format: Patent
Sprache:eng
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:1510765 Piperidinoalkylindoles BOEHRINGER MANNHEIM GmbH 4 Nov 1976 [7 Nov 1975] 45918/76 Heading C2C The invention comprises compounds of formula and their pharmacologically compatible salts, wherein R 1 , R 2 and R 3 are each H or C 1-6 alkyl, or R 3 may be halogen or C 1-6 alkoxy, and X is C 2 or C 3 alkylene. In examples, these compounds are prepared by either reacting a 3-bromoalkyl- or toxyloxyalkylindole with a 4-phenoxymethylpiperidine or introducing R 1 = alkyl. Therapeutic compositions having antihypertensive activity comprise compounds of the above formula, and may be administered orally or parenterally.