SYSTEM AND METHOD FOR EVALUATING ANTILEPROTIC ACTIVITIES BY DRUG REPURPOSING AND CHEMOTHERAPY WITH DRUG RESCUED MOLECULES

SYSTEM AND METHOD FOR EVALUATING ANTILEPROTIC ACTIVITIES BY DRUG REPURPOSING AND CHEMOTHERAPY WITH DRUG RESCUED MOLECULES

A system (100) and method (200) for evaluating antileprotic activities by drug repurposing and chemotherapy with drug rescued molecules, comprises of: a collecting unit (102) for taking crystal structure of a pharmaceutical antileprotic drug molecule; a molecular visualizer (104) to load the molecul...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: MEENALOTCHINI GURUNTHALINGAM, SREE SUDHA TANGUTURI YELLA, KOTA SESHA BRAHMA SREE KRISHNA SASANKA, ESWARAN THANGARAJU, SAJITHA VENKATESAN, ELAVARASAN KANDASAMY, PRAKASH SRINIVASAN TIMIRI SHANMUGAM, VIJAYAKUMAR ARUMUGAM RAMAMURTHY, TAMILSELVAN THANGARAJU, PUGAZHENTHAN THANGARAJU
Format: Patent
Sprache:eng
Online-Zugang:Volltext bestellen
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:A system (100) and method (200) for evaluating antileprotic activities by drug repurposing and chemotherapy with drug rescued molecules, comprises of: a collecting unit (102) for taking crystal structure of a pharmaceutical antileprotic drug molecule; a molecular visualizer (104) to load the molecule for analyzing energy associated with the crystal structure; and a controlling unit (106) for minimizing the energy to obtain stable local minima, wherein a binding activity of the crystal structure is analyzed by combination of chemotherapy with the drug molecule to dock the molecules.