ANTIBODY TARGETING CD47 AND APPLICATION THEREOF
The present invention relates to the field of biomedicine, and in particular to an antibody targeting CD47 and an application thereof. The provided anti-CD47 antibody can specifically bind to tumor cells and block human SIRPa and human CD47 signaling and can promote the phagocytosis of macrophages f...
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| Format: | Patent |
| Sprache: | eng |
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| Zusammenfassung: | The present invention relates to the field of biomedicine, and in particular to an antibody targeting CD47 and an application thereof. The provided anti-CD47 antibody can specifically bind to tumor cells and block human SIRPa and human CD47 signaling and can promote the phagocytosis of macrophages for tumor cells. The antibody has high affinity, strong specificity and good safety, would not cause red cell agglutination, and represents extremely weak binding to RBC and platelets. |
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