METHOD FOR PREPARING CRYSTALLINE PARTICLES OF 1-(3-CYANO-1-ISOPROPYL-INDOLE-5-YL)PYRAZOLE-4-CARBOXYLIC ACID, AND PHARMACEUTICAL COMPOSITION COMPRISING SAME

The present invention relates to a pharmaceutical composition comprising crystalline particles comprising a compound of chemical formula 1, comprising a compound of chemical formula 2 below by 0.2 weight% or less, or pharmaceutically acceptable salts thereof. The crystalline particles according to the present invention have optimal size, shape and distribution to be input to a preparation process of a finished preparation, have enhanced uniformity and flowability to increase the content uniformity in a preparation process of a finished pharmaceutical preparation, minimize damage during tabletting, and thus can be used as a raw pharmaceutical material suitable for a preparation process of a finished pharmaceutical preparation.