HISTONE DEACETYLASE INHIBITORS FOR IMMUNOMODULATION IN TUMOR MICROENVIRONMENT

HISTONE DEACETYLASE INHIBITORS FOR IMMUNOMODULATION IN TUMOR MICROENVIRONMENT

Provided are compounds class I HDAC inhibitors, their production and applications. The compounds possess epigenetic immunomodulatory activities in the tumor microenvironment (TME) and thus inhibit growth of tumor cells.

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Bibliographische Detailangaben
Hauptverfasser: CHENG-HAN CHOU, SZ-HAO CHU, MU-HSUAN YANG, YI-HONG WU, CHIA-NAN CHEN, JIA-SHIONG CHEN, YE-SU CHAO
Format: Patent
Sprache:eng
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Zusammenfassung:Provided are compounds class I HDAC inhibitors, their production and applications. The compounds possess epigenetic immunomodulatory activities in the tumor microenvironment (TME) and thus inhibit growth of tumor cells.