MTORC MODULATORS AND USES THEREOF

MTORC MODULATORS AND USES THEREOF

Novel rapamycin analogs and uses thereof are disclosed herein. The rapamycin analogs of the present disclosure show increased mTORC1 specificity and lowered mTORC2 specificity relative to rapamycin.

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Bibliographische Detailangaben
Hauptverfasser: STELIOS T TZANNIS, GUILLAUME EPPE, ALEXANDRE FROIDBISE, IAN J MASSEY
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:Novel rapamycin analogs and uses thereof are disclosed herein. The rapamycin analogs of the present disclosure show increased mTORC1 specificity and lowered mTORC2 specificity relative to rapamycin.