METHODS, PROCESSES AND INTERMEDIATES FOR PREPARING CHROMAN COMPOUNDS

METHODS, PROCESSES AND INTERMEDIATES FOR PREPARING CHROMAN COMPOUNDS

This disclosure describes an economical and scalable method and process to synthesize the Calcium sensing receptor (CaSR) modulating agent 2-methyl-5-((2R,4S)-2-(((R)-1-(naphthalen-1-yl)ethyl)amino)methyl)chroman-4-yl)benzoic acid, its intermediates and pharmaceutically acceptable salts therefor. Us...

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Hauptverfasser: KAMLESH JYOTINDRA PADIYA, BARVE SITARAM RAMBHAU, KUMAR RAM NAIK, RAJENDER KUMAR KAMBOJ, KAMALAKANNAN PRABAKARAN, DATTATRAY KARCHE AMIT, GANPATI POWAR RAJENDRA, SUBHASH INGAWALE SACHIN, SHANKAR DANGE SANTOSHKUMAR, BHAVANI SHANKAR RAJESH
Format: Patent
Sprache:eng
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Zusammenfassung:This disclosure describes an economical and scalable method and process to synthesize the Calcium sensing receptor (CaSR) modulating agent 2-methyl-5-((2R,4S)-2-(((R)-1-(naphthalen-1-yl)ethyl)amino)methyl)chroman-4-yl)benzoic acid, its intermediates and pharmaceutically acceptable salts therefor. Uses of said intermediates for synthesis of compounds which may be intermediates to the synthesis of 2-methyl-5-((2R,4S)-2-(((R)-1-(naphthalen-1-yl)ethyl)amino)methyl)chroman-4-yl)benzoic acid are also described herein.