SUBSTITUTED NUCLEOSIDE ANALOGS AS PRMT5 INHIBITORS

SUBSTITUTED NUCLEOSIDE ANALOGS AS PRMT5 INHIBITORS

The invention relates to substituted nucleoside analogues of formula (I), pharmaceutically acceptable salts thereof and pharmaceutical compositions for treating diseases, disorders or conditions associated with the overexpression of PRMT5 enzyme. The invention also relates to methods of treating dis...

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Hauptverfasser: NAIR, Prathap Sreedharan, PALLE, Venkata P, BHAGWAT, Shankar Bhaskar, YADAV, Amol Maruti, GUDADE, Ganesh Bhausaheb, KAMBOJ, Rajender Kumar, SINDKHEDKAR, Milind Dattatraya, KULKARNI, Chaitanya Prabhakar
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creator NAIR, Prathap Sreedharan
PALLE, Venkata P
BHAGWAT, Shankar Bhaskar
YADAV, Amol Maruti
GUDADE, Ganesh Bhausaheb
KAMBOJ, Rajender Kumar
SINDKHEDKAR, Milind Dattatraya
KULKARNI, Chaitanya Prabhakar
description The invention relates to substituted nucleoside analogues of formula (I), pharmaceutically acceptable salts thereof and pharmaceutical compositions for treating diseases, disorders or conditions associated with the overexpression of PRMT5 enzyme. The invention also relates to methods of treating diseases, disorders or conditions associated with the overexpression of PRMT5 enzyme.
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title SUBSTITUTED NUCLEOSIDE ANALOGS AS PRMT5 INHIBITORS
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