SUBSTITUTED NUCLEOSIDE ANALOGS AS PRMT5 INHIBITORS

The invention relates to substituted nucleoside analogues of formula (I), pharmaceutically acceptable salts thereof and pharmaceutical compositions for treating diseases, disorders or conditions associated with the overexpression of PRMT5 enzyme. The invention also relates to methods of treating dis...

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Bibliographische Detailangaben
Hauptverfasser:	NAIR, Prathap Sreedharan, PALLE, Venkata P, BHAGWAT, Shankar Bhaskar, YADAV, Amol Maruti, GUDADE, Ganesh Bhausaheb, KAMBOJ, Rajender Kumar, SINDKHEDKAR, Milind Dattatraya, KULKARNI, Chaitanya Prabhakar
Format:	Patent
Sprache:	eng
Online-Zugang:	Volltext bestellen
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Beschreibung
Zusammenfassung:	The invention relates to substituted nucleoside analogues of formula (I), pharmaceutically acceptable salts thereof and pharmaceutical compositions for treating diseases, disorders or conditions associated with the overexpression of PRMT5 enzyme. The invention also relates to methods of treating diseases, disorders or conditions associated with the overexpression of PRMT5 enzyme.