COMPOSITIONS AND METHODS FOR TREATING LIVER DISEASE

Disclosed are compositions and methods for treating a liver disease in a subject by increasing transport or retention of HNF4α, a transcriptional factor, into a nucleus of a hepatocyte in the subject. In some embodiments, the method comprises upregulating expression or function of one or more transc...

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Hauptverfasser: SARAH HAINER, ALEJANDRO SOTO GUTIERREZ, AARON BELL, JORGE GUZMAN LEPE, EDGAR NAOE TAFALENG, NICOLAS FRAUNHOFFER NAVARRO, GEORGE K MICHALOPOULOS, IRA FOX, ALINA OSTROWSKA, KAZUKI TAKEISHI
Format: Patent
Sprache:eng
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