LIPOSOMIAL EYE DROPS SOLUTION AND USES THEREOF FOR THE TREATMENT OF DRY EYE SYNDROME

- Ophthalmic formulations and uses thereof, for the treatment of dry eye syndrome, wherein an eye drops solution is composed of liposomes built with non hydrogenated phospholipids containing Linseed oil, Vitamin A Palmitate, Vitamin E TPGS and in water phase Vitamin B12 and Pycnogenol.- The presence of Pycnogenols increases the antioxidant capacity in external water phase and the presence of Vitamin E TPGS increases the antioxidant effect on lipophilic phase of liposomes.- The presence of Vitamin E TPGS, inside the liposomes, combined with the presence of Pycnogenol and Vitamin B12 outside the liposomes, have a protective effect (shield) against UV A/UVB rays.- It is further object of the invention, a liposomal eyes drops solution as above described, containing a specific and peculiar system composed of 2-Amino-2(hydroxymethyl) propane-1,3-diol, that act as salt forming agent for Pycnogenol (sparkly water soluble) and borate buffer, in order to improve the filterability of liposomes and have a satisfying filtration procedure to sterilize liposomial eyes drops only by filtration at 0.2 micron, avoiding the steam sterilization that would destroy the other components and liposomes structure.