INDOLINONE COMPOUNDS FOR USE AS MAP4K1 INHIBITORS

INDOLINONE COMPOUNDS FOR USE AS MAP4K1 INHIBITORS

The present disclosure is directed to compounds of formula (I) and pharmaceutically acceptable salts thereof, wherein ring A, ring C, X1, X2, L1, R1, R2, R3, R4, R5, R6, R7, m and n are as defined herein, which are useful as MAP4K1 inhibitors, processes for their preparation, pharmaceutical composit...

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Bibliographische Detailangaben
Hauptverfasser: DHONE, Sachin, Vasantrao, CHAUDHARI, Sachin Sundarlal, ADIK, Bharat, Gangadhar, GHARAT, Laxmikant, Atmaram, WADEKAR, Prashant, Dilip, IYER, Pravin, GOWDA, Nagaraj, BAJPAI, Malini
Format: Patent
Sprache:eng
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Zusammenfassung:The present disclosure is directed to compounds of formula (I) and pharmaceutically acceptable salts thereof, wherein ring A, ring C, X1, X2, L1, R1, R2, R3, R4, R5, R6, R7, m and n are as defined herein, which are useful as MAP4K1 inhibitors, processes for their preparation, pharmaceutical compositions comprising the compounds, and the use of the compounds or the compositions in the treatment or prevention of various diseases, conditions and/or disorders mediated by MAP4K1.