FUMARATE SALT OF 5-((5-METHYL-2-((3,4,5-TRIMETHYLPHENYL)AMINO)PYRIMIDIN-4-YL)AMINO)-BENZO[D]OXAZOL-2(3H)-ONE

FUMARATE SALT OF 5-((5-METHYL-2-((3,4,5-TRIMETHYLPHENYL)AMINO)PYRIMIDIN-4-YL)AMINO)-BENZO[D]OXAZOL-2(3H)-ONE

A fumarate salt, in particular the hemi-fumarate salt, of 5-((5-methyl-2-((3,4,5-trimethylphenyl)amino)pyrimidin-4-yl)amino)-benzo[d]oxazol-2(3H)-one (Compound (I), compositions comprising such a salt, and processes for the manufacture of such a salt, in particular Compound (I) hemi-fumarate salt ar...

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Bibliographische Detailangaben
Hauptverfasser: SMITH, Reed Warren, SCHULZ, Håkan
Format: Patent
Sprache:eng
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Zusammenfassung:A fumarate salt, in particular the hemi-fumarate salt, of 5-((5-methyl-2-((3,4,5-trimethylphenyl)amino)pyrimidin-4-yl)amino)-benzo[d]oxazol-2(3H)-one (Compound (I), compositions comprising such a salt, and processes for the manufacture of such a salt, in particular Compound (I) hemi-fumarate salt are described. The salt is useful for the treatment of conditions such as asthma and COPD, involving modulation of the JAK pathway or inhibition of JAK kinases particularly JAK1.