ANTIBODIES BINDING CTLA-4 AND USES THEREOF

ANTIBODIES BINDING CTLA-4 AND USES THEREOF

Disclosed are isolated monoclonal antibodies, comprising a CD152-binding domain, wherein the antibodies bind specifically to human CD152. Methods of making and using the antibodies to treat diseases including cancers and autoimmune diseases are also provided.

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Bibliographische Detailangaben
Hauptverfasser: YUQIANG SHEN, XIN GAN, YUN HE, JIUQIAO ZHAO, MARINUS (RIEN) VAN HAPEREN, YIPING RONG, DUBRAVKA DRABEK, RICK JANSSENS, FRANK GROSVELD
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:Disclosed are isolated monoclonal antibodies, comprising a CD152-binding domain, wherein the antibodies bind specifically to human CD152. Methods of making and using the antibodies to treat diseases including cancers and autoimmune diseases are also provided.