LIPOSOMAL FORMULATIONS COMPRISING SAPONIN AND METHODS OF USE

Provided herein are liposomal formulations containing saponin and optionally, a lipopolysaccharide. Also provided IC herein are pharmaceutical compositions and vaccine compositions comprising the liposomal formulations and an antigen. The pharmaceutical compositions and vaccine compositions are capa...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: FOX, Christopher B, LIN, Susan S
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:Provided herein are liposomal formulations containing saponin and optionally, a lipopolysaccharide. Also provided IC herein are pharmaceutical compositions and vaccine compositions comprising the liposomal formulations and an antigen. The pharmaceutical compositions and vaccine compositions are capable of eliciting or enhancing of an immune response, for example, for vaccine or therapeutic uses. Compositions and methods related to making the liposomal formulations and using the liposomal formulations for eliciting or enhancing an immune response are also provided.