GLYCYRRHETINIC ACID DERIVATIVES FOR TREATING HYPERKALEMIA

GLYCYRRHETINIC ACID DERIVATIVES FOR TREATING HYPERKALEMIA

The present invention provides a compound of formula (I) or a salt thereof: (I) wherein X, L, V, R1, R2, R3 and R4, are as defined herein. These compounds are inhibitors of 11-hydroxysteroid dehydrogenase type 2 (11-HSD-2) and are used to treat hyperkalemia.

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Bibliographische Detailangaben
Hauptverfasser: LUEHR, Gary, CHEN, Tao, DRAGOLI, Dean, LEWIS, Jason, LEADBETTER, Michael
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:The present invention provides a compound of formula (I) or a salt thereof: (I) wherein X, L, V, R1, R2, R3 and R4, are as defined herein. These compounds are inhibitors of 11-hydroxysteroid dehydrogenase type 2 (11-HSD-2) and are used to treat hyperkalemia.