NOVEL TEBIPENEM PIVOXIL IMMEDIATE AND MODIFIED RELEASE ORAL DOSAGE FORMS

NOVEL TEBIPENEM PIVOXIL IMMEDIATE AND MODIFIED RELEASE ORAL DOSAGE FORMS

Immediate and modified release oral dosage forms of tebipenem pivoxil including dosage form cores are provided. The disclosure includes tebipenem pivoxil HBr tablets comprising at least 55% (w/w) tebipenem pivoxil. The dosage forms may include excipients including a binder, a lubricant, optionally a...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: SHOUFENG LI, SHAOQIONG LYU, ENXIAN LU, TIMOTHY KEUTZER, LUKE UTLEY, GRAZYNA FRACZKIEWICZ, JOYCE MACWAN, AKASH JAIN
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:Immediate and modified release oral dosage forms of tebipenem pivoxil including dosage form cores are provided. The disclosure includes tebipenem pivoxil HBr tablets comprising at least 55% (w/w) tebipenem pivoxil. The dosage forms may include excipients including a binder, a lubricant, optionally a diluent, and optionally additional excipients. The disclosure also includes the disclosed dosage forms for use in treating bacterial infections including complicated urinary tract infections.