MODULATOR OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR, PHARMACEUTICAL COMPOSITIONS, METHODS OF TREATMENT, AND PROCESS FOR MAKING THE MODULATOR

MODULATOR OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR, PHARMACEUTICAL COMPOSITIONS, METHODS OF TREATMENT, AND PROCESS FOR MAKING THE MODULATOR

Compounds of Formula I:pharmaceutically acceptable salts thereof, deuterated derivatives of any of the foregoing, and metabolites of any of the foregoing are disclosed. Pharmaceutical compositions comprising the same, methods of treating cystic fibrosis using the same, and methods for making the sam...

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Hauptverfasser: ANDREAS P TERMIN, VITO MELILLO, FREDRICK VAN GOOR, FABRICE JEAN DENIS PIERRE, BRETT BRADLEY BUSCH, PRASUNA PARASELLI, ALI KESHAVARZ-SHOKRI, THOMAS CLEVELAND, ALEXANDER RUSSELL ABELA, JOHNNY UY, TIMOTHY ALCACIO, PRAMOD VIRUPAX JOSHI, PAUL JOHN KRENITSKY, PETER GROOTENHUIS, ROBERT M HUGHES, SARA SABINA HADIDA RUAH, JASON MCCARTNEY, MINSON BAEK, RACHEL MCAULEY-AOKI, DAVID ANDREW SIESEL, JINGLAN ZHOU, MARK THOMAS MILLER, BEILI ZHANG, BRYAN A FRIEMAN, HARIPADA KHATUYA, COREY ANDERSON
Format: Patent
Sprache:eng
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Zusammenfassung:Compounds of Formula I:pharmaceutically acceptable salts thereof, deuterated derivatives of any of the foregoing, and metabolites of any of the foregoing are disclosed. Pharmaceutical compositions comprising the same, methods of treating cystic fibrosis using the same, and methods for making the same are also disclosed.