INSULIN ANALOGS

The present invention relates to insulin analogs, particularly insulin analogs having shortened B chains. The present invention also relates to the crystal structure of insulin from the venom of cone snails and to methods of using the crystal and related structural information to screen for and desi...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser:	JOHN GERBRANDT TASMAN MENTING, MICHAEL COLIN LAWRENCE, BRIAN SMITH, OLIVERA M BALDOMERO, HELENA SAFAVI-HEMAMI, DANNY HUNGIEH CHOU
Format:	Patent
Sprache:	eng
Online-Zugang:	Volltext bestellen
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Beschreibung
Zusammenfassung:	The present invention relates to insulin analogs, particularly insulin analogs having shortened B chains. The present invention also relates to the crystal structure of insulin from the venom of cone snails and to methods of using the crystal and related structural information to screen for and design insulin analogs that interact with or modulate the insulin receptor. The present invention also relates to therapeutic and prophylactic methods using insulin analogs.