A NOVEL IL33 FORM, MUTATED FORMS OF IL33, ANTIBODIES, ASSAYS AND METHODS OF USING THE SAME

A NOVEL IL33 FORM, MUTATED FORMS OF IL33, ANTIBODIES, ASSAYS AND METHODS OF USING THE SAME

The present invention provides isolated IL-33 proteins, active fragments thereof and antibodies, antigen binding fragments thereof, against IL-33 proteins. Also provided are methods of modulating cytokine activity, e.g., for the purpose of treating immune and inflammatory disorders.

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Hauptverfasser: ENGLAND, Elizabeth H, STRAIN, Martin D, LOWE, David Christopher, SCOTT, Ian C, COHEN, Emma Suzanne, BUTLER, Robin, CARMEN, Sara, OVERED-SAYER, Catherine L, HOUSLAY, Kirsty, KEMP, Benjamin P, SLEEMAN, Matthew, VOUSDEN, Katherine A, REES, David G, MUSTELIN, Tomas M
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creator ENGLAND, Elizabeth H
STRAIN, Martin D
LOWE, David Christopher
SCOTT, Ian C
COHEN, Emma Suzanne
BUTLER, Robin
CARMEN, Sara
OVERED-SAYER, Catherine L
HOUSLAY, Kirsty
KEMP, Benjamin P
SLEEMAN, Matthew
VOUSDEN, Katherine A
REES, David G
MUSTELIN, Tomas M
description The present invention provides isolated IL-33 proteins, active fragments thereof and antibodies, antigen binding fragments thereof, against IL-33 proteins. Also provided are methods of modulating cytokine activity, e.g., for the purpose of treating immune and inflammatory disorders.
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title A NOVEL IL33 FORM, MUTATED FORMS OF IL33, ANTIBODIES, ASSAYS AND METHODS OF USING THE SAME
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