A NOVEL IL33 FORM, MUTATED FORMS OF IL33, ANTIBODIES, ASSAYS AND METHODS OF USING THE SAME

A NOVEL IL33 FORM, MUTATED FORMS OF IL33, ANTIBODIES, ASSAYS AND METHODS OF USING THE SAME

The present invention provides isolated IL-33 proteins, active fragments thereof and antibodies, antigen binding fragments thereof, against IL-33 proteins. Also provided are methods of modulating cytokine activity, e.g., for the purpose of treating immune and inflammatory disorders.

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: ENGLAND, Elizabeth H, STRAIN, Martin D, LOWE, David Christopher, SCOTT, Ian C, COHEN, Emma Suzanne, BUTLER, Robin, CARMEN, Sara, OVERED-SAYER, Catherine L, HOUSLAY, Kirsty, KEMP, Benjamin P, SLEEMAN, Matthew, VOUSDEN, Katherine A, REES, David G, MUSTELIN, Tomas M
Format: Patent
Sprache:eng
Online-Zugang:Volltext bestellen
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:The present invention provides isolated IL-33 proteins, active fragments thereof and antibodies, antigen binding fragments thereof, against IL-33 proteins. Also provided are methods of modulating cytokine activity, e.g., for the purpose of treating immune and inflammatory disorders.