PHARMACEUTICAL COMPOSITIONS OF A ERB2 (HER2) INHIBITOR

PHARMACEUTICAL COMPOSITIONS OF A ERB2 (HER2) INHIBITOR

A solid dispersion of N4-(4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)-3-methylphenyl)-N6-(4,4-dimethyl-4,5-dihydrooxazol-2-yl)quinazoline-4,6-diamine and processes for preparing the solid dispersion are provided herein. Also, a pharmaceutical composition comprising a solid dispersion of N4-(4-([1,2,4]...

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Bibliographische Detailangaben
Hauptverfasser: FRY, David Shank, CRAIG, Christopher Donovan, GAUTSCHI, Jeff, PREIGH, Michael, LINDEMANN, Christopher M, BLOOM, Corey Jay, SMITHEY, Dan, DUBOSE, Devon Brevard
Format: Patent
Sprache:eng
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Zusammenfassung:A solid dispersion of N4-(4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)-3-methylphenyl)-N6-(4,4-dimethyl-4,5-dihydrooxazol-2-yl)quinazoline-4,6-diamine and processes for preparing the solid dispersion are provided herein. Also, a pharmaceutical composition comprising a solid dispersion of N4-(4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)-3-methylphenyl)-N6-(4,4-dimethyl-4,5-dihydrooxazol-2-yl)quinazoline-4,6-diamine and uses thereof are provided herein.