CYANOTRIAZOLE COMPOUNDS

This invention relates to a cyanotriazole compound represented by the formula (1):wherein each symbols are defined in the specification,or a salt thereof. The compound or a salt thereof stimulates the citric acid cycle activity and/or improves hyperglycemia with less side effects, and excellent safe...

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Bibliographische Detailangaben
Hauptverfasser: SHINOHARA, Toshio, SAKURAI, Yohji, MATSUMURA, Chiharu, SATO, Seiji, KANEMOTO, Naohide, FUJITA, Shigekazu, TAI, Kuninori, OKAMOTO, Takashi, ITOTANI, Motohiro, MATSUDA, Satoshi, FUKUSHIMA, Tae
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:This invention relates to a cyanotriazole compound represented by the formula (1):wherein each symbols are defined in the specification,or a salt thereof. The compound or a salt thereof stimulates the citric acid cycle activity and/or improves hyperglycemia with less side effects, and excellent safety, and therefore, it is useful for treating and/or preventing diseases or disorders on which citric acid cycle activation and/or improvement of hyperglycemia has a prophylactic and/or therapeutic effect, for example, diabetes, impaired glucose tolerance, insulin resistance, diabetic complications, obesity, dyslipidemia, hepatic steatosis, atherosclerosis and/or cardiovascular disease, as well as diseases or disorders that would benefit from stimulating energy expenditure.